Anonymous 11/18/2023 (Sat) 21:06 No.106317 del
>>106195
>У меня была мечта — разработать доступный метод синтеза триптаминов

SYNTHESIS: (from tryptamine) A solution of 1.6 g tryptamine base in 10 mL isopropanol was treated with 5.1 g propyl iodide and 5.2 g diisopropylethyl amine, and stirred at room temperature for 36 h. The volatiles were removed under vacuum, and the residue was partitioned between CH2Cl2 and H2O made basic with NaOH. The organic phase was separated, the aqueous phase extracted with two additional portions of CH2Cl2, the extracts pooled and the solvent removed under vacuum. The residue, a fluid brown oil weighing 2.75 g, was treated with 5 g acetic anhydride and heated on the steam bath for 20 min. After cooling, a small amount of ammonium hydroxide was added, and the mixture added to 200 mL 0.5 N H2SO4. This aqueous solution was washed three times with CH2Cl2 and then made basic with 25% NaOH. This was extracted with 3×40 mL CH2Cl2, the extracts pooled, and the solvent removed under vacuum. The oily residue was distilled at 145–155 °C at 0.08 mm/Hg to give 1.14 g N,N-dipropyltryptamine base as a white oil.

Что из этого недоступно кроме йодпропана(который скорее всего можно заменить хлорпропаном)? Собираюсь летом как закрою сессию попробовать.